NFL Week 6 picks, odds
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NFL Week 6 picks, odds

Football handicapper Sean Treppedi is in his first season in The Post’s NFL Bettor’s Guide. 

PATRIOTS (+7) Over Texans

I always expect a galvanizing response following an embarrassing loss and a quarterback change.

It’s easy to fade a rookie under center against a Texans team that just conquered Josh Allen and the Bills, just keep in mind that as a favorite of three points or more, C.J. Stroud is 2-7 ATS — the worst mark in the NFL since he was drafted in 2023.

He’s never closed as a seven-point favorite. 

The verdict will be out on Drake Maye, but he’s supported by a backfield that has produced 4.9 yards per attempt.

Fortunately, the Texans are tied for having coughed up the eighth-most rushing yards.

Oddsmakers are simply overvaluing Houston, which is 1-3-1 ATS with two one-possession wins, against the Bears and Jaguars. 


Denver Broncos quarterback Bo Nix (10) warms up before the game against the Las Vegas Raiders at Empower Field at Mile High. USA TODAY Sports via Reuters Con

Broncos (+2.5) Over CHARGERS

Maybe we don’t know Bo.

The rookie is rolling off his third straight win, a game in which he completed 70 percent of his passes and collected three total touchdowns.

He hasn’t thrown an interception since Week 2, and now he draws a Chargers secondary that is allowing the league’s second-friendliest completion rate of 72.5 percent. 

This Chargers offense is a fragile work in progress.


Betting on the NFL?


Jim Harbaugh loves milking the clock, operating the slowest offense in seconds per play.

The Broncos can cause disruption with the second-most aggressive blitz in the NFL.

As underdogs, Sean Payton’s teams have covered at a 61 percent rate dating back to 1990. Since 2019, he’s 5-1 straight up against teams off extended rest when his is not. 

Last week: 1-1. Cardinals (W). Seahawks (L)
Season: 6-4.

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